3-Chloro-2-nitroaniline
- CAS: 59483-54-4
- Purity: 99%
- Chemical plants supply high-quality 3-Chloro-2-nitroaniline 59483-54-4 in bulk
Chemical plants supply high-quality 3-Chloro-2-nitroaniline 59483-54-4 in bulk
- Molecular Formula: C6H5ClN2O2
- Molecular Weight: 172.571
- Appearance/Colour: orange/tan solid
- Vapor Pressure: 0.000207mmHg at 25°C
- Melting Point: 107-108 °C
- Refractive Index: 1.646
- Boiling Point: 327.1 °C at 760 mmHg
- PKA: -1.29±0.10(Predicted)
- Flash Point: 151.6 °C
- PSA： 71.84000
- Density: 1.494 g/cm3
- LogP: 2.93480
3-Chloro-2-nitroaniline(Cas 59483-54-4) Usage
InChI:InChI=1/C6H5ClN2O2/c7-4-2-1-3-5(8)6(4)9(10)11/h1-3H,8H2
59483-54-4 Relevant articles
NRF2 REGULATORS
-
Page/Page column 273, (2015/07/07)
The present invention relates to bis ary...
Identification of novel HDAC inhibitors through cell based screening and their evaluation as potential anticancer agents
Wang, Tong,Sepulveda, Mario,Gonzales, Paul,Gately, Stephen
, p. 4790 - 4793 (2013/09/02)
A series of benzimidazole based HDAC inh...
Synthesis and potent antifungal activity against Candida species of some novel 1H-benzimidazoles
Goeker, Hakan,Alp, Mehmet,Ates-Alagoez, Zeynep,Yildiz, Sulhiye
scheme or table, p. 936 - 948 (2009/12/05)
(Chemical Equation Presented) A series o...
C-6 RING-SUBSTITUTED PYRIDO[1,2-a]BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS
-
Page/Page column 5; 6, (2008/06/13)
A C-6 ring-substituted pyrido[1,2-a]benz...
59483-54-4 Process route
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-
4771-47-5
3-chloro-2-nitro-benzoic acid
-
-
59483-54-4
3-chloro-2-nitro-aniline
| Conditions | Yield |
|---|---|
|
With
diphenyl phosphoryl azide; triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 3h;
|
53.4%
|
|
Multistep reaction;
(i) NaN3, SO3/H2SO4, (ii) H2O;
|
|
|
Multi-step reaction
with
4
steps
1: SOCl2
/ 3 h / Heating
2: NaN3
/ acetone; H2
O / 0.5 h / Ambient temperature
3: benzene / Heating
4: 5 N aq. NaOH / benzene / 1 h / Ambient temperature
With
sodium hydroxide; thionyl chloride; sodium azide;
In
water; acetone; benzene;
|
|
|
Multi-step reaction
with
3
steps
1: 51.1 g / thionyl chloride / toluene / 3 h / Heating
2: 96 percent / 28percent aq. NH3
/ 0.33 h
3: 1.) Br2
, 2.) KOH / 1.) water, 30 min, 0 deg C, 2.) water, 70-75 deg C, 45 min
With
potassium hydroxide; ammonium hydroxide; thionyl chloride; bromine;
In
toluene;
|
|
|
With
sodium azide; sulfuric acid;
|
|
|
With
sodium azide; sulfuric acid; sulfur trioxide;
|
|
|
With
sodium azide; sulfuric acid; sulfur trioxide;
|
-
-
601-88-7
2,6-dichloronitrobenzene
-
-
59483-54-4
3-chloro-2-nitro-aniline
| Conditions | Yield |
|---|---|
|
With
ammonium hydroxide;
at 150 ℃;
for 240h;
|
61%
|
|
With
ammonia; water;
at 200 ℃;
|
|
|
With
ammonium hydroxide;
In
ethanol;
at 150 ℃;
for 336h;
|
81 % Turnov.
|
59483-54-4 Upstream products
-
64-17-5
ethanol
-
602-02-8
2,3-dinitrochlorobenzene
-
601-88-7
2,6-dichloronitrobenzene
-
99233-27-9
N-(3-chloro-2-nitrophenyl)acetamide
59483-54-4 Downstream products
-
105905-40-6
bis-(3-chloro-2-nitro-phenyl)-diazene
-
131885-46-6
3-(1-Imidazolyl)-2-nitroaniline
-
149156-05-8
3-chloro-2-nitro-N-formylaniline
-
141816-10-6
3-chloro-2-nitro-N,N-dimethylaniline
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