1,1-diethoxy-3-phenylacetone
- CAS: 19256-31-6
- Purity: 99%
- Factory supply 1,1-diethoxy-3-phenylacetone 19256-31-6 with low price
Factory supply 1,1-diethoxy-3-phenylacetone 19256-31-6 with low price
- Molecular Formula: C13H18 O3
- Molecular Weight: 222.284
- Vapor Pressure: 0.000188mmHg at 25°C
- Boiling Point: 328.6°Cat760mmHg
- Flash Point: 143.6°C
- Density: 1.033g/cm3
1,1-diethoxy-3-phenylacetone(Cas 19256-31-6) Usage
|
General Description |
1,1-diethoxy-3-phenylacetone, also known as 1,1-diethoxypropiophenone, is a chemical compound used as an organic synthesis reagent in the creation of various pharmaceutical drugs. It belongs to the class of chemicals called organic esters, characterized by a carbon-oxygen double bond. 1,1-diethoxy-3-phenylacetone plays a crucial role as an intermediate in the manufacturing process of drugs, including several antipsychotic medications. It is crucial to handle this chemical with care, as it can cause skin and eye irritation, and even serious eye damage. Moreover, it is recommended to avoid breathing in this compound, as it might cause respiratory irritation. |
InChI:InChI=1/C13H18O3/c1-3-15-13(16-4-2)12(14)10-11-8-6-5-7-9-11/h5-9,13H,3-4,10H2,1-2H3
19256-31-6 Relevant articles
A convenient method for the preparation of α-ketoacetals
Adamczyk, Maciej,Johnson, Donald D.,Mattingly, Phillip G.,Pan, You,Reddy, Rajarathnam E.
, p. 3199 - 3205 (2002)
A convenient method for the preparation ...
Bisdeoxycoelenterazine derivatives for improvement of bioluminescence resonance energy transfer assays
Levi, Jelena,De, Abhijit,Cheng, Zhen,Gambhir, Sanjiv Sam
, p. 11900 - 11901 (2007)
We report here syntheses of bisdeoxycoel...
Deuterated compound based on cavity enterostatin - h as well as preparation method and application thereof
-
Paragraph 0028; 0066; 0073-0074, (2021/11/26)
The invention discloses a deuterated com...
HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSTION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT
-
Paragraph 0729-0731, (2018/04/26)
The present invention relates to a heter...
New bioluminescent coelenterazine derivatives with various C-6 substitutions
Jiang, Tianyu,Yang, Xingye,Zhou, Yubin,Yampolsky, Ilia,Du, Lupei,Li, Minyong
, p. 7008 - 7018 (2017/09/01)
A series of new coelenterazine analogs w...
Luminescence of coelenterazine derivatives with C-8 extended electronic conjugation
Yuan, Ming-Liang,Jiang, Tian-Yu,Du, Lu-Pei,Li, Min-Yong
supporting information, p. 550 - 554 (2016/04/26)
Replacement of the methylene group at th...
19256-31-6 Process route
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-
6921-34-2
benzylmagnesium chloride
-
-
6065-82-3
Ethyl diethoxyacetate
-
-
19256-31-6
1,1-diethoxy-3-phenylpropane-2-one
| Conditions | Yield |
|---|---|
|
In
tetrahydrofuran;
at -78 ℃;
for 2h;
|
96%
|
|
In
tetrahydrofuran;
at -78 ℃;
for 12h;
|
93%
|
|
In
tetrahydrofuran;
at -78 ℃;
for 2h;
|
91.8%
|
|
In
tetrahydrofuran; diethyl ether;
at -78 ℃;
for 2h;
Inert atmosphere;
|
90.6%
|
|
benzylmagnesium chloride; Ethyl diethoxyacetate;
In
tetrahydrofuran; diethyl ether;
at -78 ℃;
for 2h;
With
water; ammonium chloride;
In
tetrahydrofuran; diethyl ether;
|
84%
|
|
In
tetrahydrofuran;
at 78 ℃;
for 2.5h;
Inert atmosphere;
|
63%
|
|
In
tetrahydrofuran;
at -78 ℃;
for 3h;
Inert atmosphere;
|
60%
|
|
In
tetrahydrofuran;
at -78 ℃;
for 3h;
Inert atmosphere;
|
60%
|
-
-
C16 H14 BF2 NO
-
-
64-17-5
ethanol
-
-
19256-31-6
1,1-diethoxy-3-phenylpropane-2-one
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
dichloromethane;
at 20 ℃;
for 12h;
|
100%
|
19256-31-6 Upstream products
-
64-17-5
ethanol
-
56485-04-2
benzylglyoxal
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6921-34-2
benzylmagnesium chloride
-
6065-82-3
Ethyl diethoxyacetate
19256-31-6 Downstream products
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70217-82-2
2-benzyl-8-benzyl-6-(phenyl)imidazo[1,2-a]pyrazin-3(7H)-one
-
931402-43-6
C25 H25 N7 O
-
1262117-93-0
2-benzyl-6-phenyl-8-(phenylthio)imidazo[1,2-a]pyrazin-3(7H)-one
-
1262118-00-2
2-benzyl-8-(4-chlorophenylthio)-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one
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